Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 3/20 | 0.37 |
| ▸ | HTR1A | P08908 | 4/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 4/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 4/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.35 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | QPCT | Q16769 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759453 | 0.89 | HDAC6 (0.55) | HDAC6KAT2BHTR1AADRA1DADRA1A | |
| SCHEMBL9759440 | 0.81 | CHRM2 (0.39) | HDAC6HDAC3HDAC1THRBTDP1 | |
| SCHEMBL8317776 | 0.79 | PTGER4 (0.51) | HDAC6KAT2BHDAC3HDAC1CYP3A4 | |
| SCHEMBL9759491 | 0.77 | CYP3A4 (0.36) | HDAC6KAT2BHTR1AADRA1DADRA1A | |
| SCHEMBL9759574 | 0.77 | NQO2 (0.41) | HDAC6KAT2BHDAC1GUCY1A1GUCY1B1 | |
| SCHEMBL2344181 | 0.77 | HDAC6 (0.49) | HDAC6KAT2BHTR1AADRA1DADRA1A | |
| SCHEMBL7136396 | 0.77 | KAT2B (0.57) | HDAC6KAT2BHTR1AADRA1DADRA1A | |
| SCHEMBL21841848 | 0.75 | HDAC6 (0.48) | HDAC6KAT2BHTR1AADRA1DADRA1A | |
| SCHEMBL14616763 | 0.75 | PTGER4 (0.50) | HDAC6HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9759837 | 0.75 | HDAC6 (0.40) | HDAC6KAT2BHTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997860-A | Amino-substituted silanediol or silanetriol | TOSHIBA SILICONE CO., LTD. (JP) | 1991-03-05 | — | — | US | disclosed |