Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 10/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9759491 | 0.87 | CYP3A4 (0.36) | CHRM2HDAC6MAPTHTTALDH1A1 | |
| SCHEMBL8029183 | 0.86 | CHRM2 (0.43) | CHRM2HDAC6MAPTHTTKDM4E | |
| SCHEMBL9759830 | 0.81 | HDAC6 (0.42) | HDAC6HTTALDH1A1THRBTDP1 | |
| SCHEMBL9759453 | 0.81 | HDAC6 (0.55) | HDAC6MAPTKDM4EALDH1A1GAA | |
| SCHEMBL16799183 | 0.79 | ALDH1A1 (0.55) | MAPTHTTKDM4EALDH1A1GAA | |
| SCHEMBL15515693 | 0.78 | CHRM2 (0.36) | CHRM2MAPTHTTKDM4E | |
| SCHEMBL215272 | 0.77 | HDAC3 (0.50) | CHRM2HDAC6MAPTHTTKDM4E | |
| SCHEMBL867417 | 0.77 | PRSS1 (0.47) | HDAC6MAPTHTTKDM4EALDH1A1 | |
| SCHEMBL9515506 | 0.77 | TLR8 (0.38) | CHRM2HDAC6MAPTHTTKDM4E | |
| SCHEMBL7745287 | 0.77 | PTGER4 (0.51) | CHRM2HDAC6MAPTHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4997860-A | Amino-substituted silanediol or silanetriol | TOSHIBA SILICONE CO., LTD. (JP) | 1991-03-05 | — | — | US | disclosed |