Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | PTPRC | P08575 | 1/20 | 0.37 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL55225 | 0.82 | GPR35 (0.55) | GPR35TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL562027 | 0.82 | HSD17B10 (0.48) | GPR35TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29595518 | 0.82 | HSD17B10 (0.48) | GPR35TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL13982688 | 0.81 | TSHR (0.41) | GPR35TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL622040 | 0.81 | GPR35 (0.53) | GPR35TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL28411146 | 0.80 | ALDH1A1 (0.47) | GPR35TSHRTDP1ALDH1A1PTPN11 | |
| SCHEMBL16951559 | 0.79 | TDP1 (0.39) | GPR35TSHRTDP1ALDH1A1PTPN11 | |
| SCHEMBL18825129 | 0.79 | TDP1 (0.45) | GPR35TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL11451783 | 0.79 | TDP1 (0.67) | GPR35TSHRTDP1ALDH1A1SMN1; SMN2 | |
| SCHEMBL1926046 | 0.79 | TSHR (0.71) | GPR35TSHRTDP1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293073-B1 | CHROMAN-6-SULPHONYL DERIVATIVES | Wendstone Chemicals P.L.C. (GB) | 1991-09-18 | — | — | EP | claimed |
| US-4582947-A | Nucleophilic displacement process for preparing 2,6-dihydrocarbonyl-4-(nitroaryl)phenol | ETHYL CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |