Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA3 | P07451 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA6 | P23280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766465 | 0.84 | MAPT (0.61) | KDM4EHTTMAPTTSHRSMN1; SMN2 | |
| SCHEMBL3093965 | 0.84 | MAPT (0.57) | KDM4EHTTMAPTTSHRSMN1; SMN2 | |
| SCHEMBL3911973 | 0.84 | RAB9A (0.57) | KDM4EHTTMAPTTSHRSMN1; SMN2 | |
| SCHEMBL3901381 | 0.84 | KDM4E (0.49) | KDM4EHTTMAPTTSHRSMN1; SMN2 | |
| SCHEMBL3095521 | 0.84 | KDM4E (0.68) | KDM4EHTTMAPTTSHRSMN1; SMN2 | |
| SCHEMBL3909813 | 0.84 | HTT (0.54) | KDM4EHTTMAPTTSHRSMN1; SMN2 | |
| SCHEMBL3400224 | 0.84 | HPGD (0.55) | KDM4EHTTMAPTTSHRSMN1; SMN2 | |
| SCHEMBL24363913 | 0.84 | CNR1 (0.54) | KDM4EHTTMAPTTSHRSMN1; SMN2 | |
| SCHEMBL3899784 | 0.83 | L3MBTL3 (0.54) | KDM4EHTTMAPTTSHRHSP90AA1 | |
| SCHEMBL17774880 | 0.83 | HSP90AA1 (0.57) | KDM4EHTTMAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5034426-A | Reaction of polyisocyanate, polyol and a chain extender which is also a catalyst because of a tert-amine side chain | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1991-07-23 | — | — | US | disclosed |
| US-4937306-A | For polyurethanes | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-06-26 | — | — | US | disclosed |
| US-4810769-A | Process of preparing polyurethanes cured with 2,6-idaminobenzoic acid derivatives and blends of the 2, 4 and 2,6 isomers | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-03-07 | — | — | US | disclosed |
| EP-0300366-A1 | Non-fugitive aromatic diamine catalytic chain extenders | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1989-01-25 | — | — | EP | disclosed |
| EP-0293845-A2 | Polyurethanes cured with 2,6-diaminobenzoic acid derivatives and blends of the 2,4 and 2,6 isomers | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1988-12-07 | — | — | EP | disclosed |
| US-4054556-A | Polyurethanes cured with derivatives of 2,4-diamino-benzoic acid | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-10-18 | — | — | US | disclosed |
| US-4039514-A | SUBSTITUTED 2,4-DIAMINOBENZOIC ACID | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-08-02 | — | — | US | disclosed |