SCHEMBL975990

SCHEMBL975990

CCOC(=O)C1(C(=O)OCC)COC2(CC(C)(C)N(OC(C)c3ccc(OCC4CO4)cc3)C(C)(C)C2)OC1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.35
ALDH1A1 P00352 3/20 0.35
TP53 P04637 2/20 0.35
HPGD P15428 2/20 0.35
TSHR P16473 2/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
CYP1A2 P05177 1/20 0.35
PPARG P37231 1/20 0.35
HIF1A Q16665 1/20 0.35
FFAR1 O14842 2/20 0.34
SMN1; SMN2 Q16637 4/20 0.33
LMNA P02545 3/20 0.33
PKM P14618 2/20 0.33
GAA P10253 1/20 0.33
ABCB11 O95342 1/20 0.32
MAPK1 P28482 1/20 0.32
GRM2 Q14416 1/20 0.32
RAB9A P51151 4/20 0.32
NPC1 O15118 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL977671 0.94 MAPT (0.32) MAPTALDH1A1TP53HPGDTSHR
SCHEMBL6874267 0.89 TDP1 (0.36) MAPTALDH1A1TP53HPGDTSHR
SCHEMBL6864558 0.88 MAPT (0.32) MAPTALDH1A1TP53HPGDTSHR
SCHEMBL6865025 0.86 TDP1 (0.36) MAPTALDH1A1TP53HPGDTSHR
SCHEMBL977824 0.86 TP53 (0.37) MAPTALDH1A1TP53HPGDTSHR
SCHEMBL975501 0.86 PKM (0.35) MAPTALDH1A1TP53HPGDTSHR
SCHEMBL12922174 0.85 ALDH1A1 (0.39) MAPTALDH1A1TP53HPGDTSHR
SCHEMBL974405 0.85 ALDH1A1 (0.39) MAPTALDH1A1TP53HPGDTSHR
SCHEMBL975816 0.85 GRM2 (0.34) MAPTALDH1A1TP53HPGDTSHR
SCHEMBL977193 0.85 ALDH1A1 (0.40) MAPTALDH1A1TP53HPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization FUSO FRANCESCO 2007-07-26 US claimed
EP-1341763-B1 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION CIBA SC HOLDING AG (CH) 2004-06-16 EP claimed
US-20040049043-A1 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization CIBA SPECIALTY CHEMICALS CORP. 2004-03-11 US claimed
EP-1341763-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION Ciba SC Holding AG (CH) 2003-09-10 EP claimed
WO-2002048109-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINES AS RADICAL POLYMERIZATION INITIATORS CIBA SPECIALTY CHEMICLAS HOLDING INC. (CH) 2002-06-20 WO claimed
US-7868171-B2 N-alkoxy-4, 4-dioxy-polyalkyl-piperidines as radical polymerization initiators CIBA SPECIALTY CHEMICALS CORP. (US) 2011-01-11 US disclosed
US-7868171-B2 N-alkoxy-4, 4-dioxy-polyalkyl-piperidines as radical polymerization initiators CIBA SPECIALTY CHEMICALS CORP. (US) 2011-01-11 US disclosed
US-7868171-B2 N-alkoxy-4, 4-dioxy-polyalkyl-piperidines as radical polymerization initiators CIBA SPECIALTY CHEMICALS CORP. (US) 2011-01-11 US disclosed
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization FUSO FRANCESCO 2007-07-26 US disclosed
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization FUSO FRANCESCO 2007-07-26 US disclosed
US-7235663-B2 N-alkoxy-4,4-dioxy-polyalkyl-piperidines as radical polymerization inhibitors CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 US disclosed
US-7235663-B2 N-alkoxy-4,4-dioxy-polyalkyl-piperidines as radical polymerization inhibitors CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 US disclosed
US-7235663-B2 N-alkoxy-4,4-dioxy-polyalkyl-piperidines as radical polymerization inhibitors CIBA SPECIALTY CHEMICALS CORP. (US) 2007-06-26 US disclosed
US-7144691-B2 Color photographic recording material CIBA SPECIALTY CHEMICALS CORPORATION (US) 2006-12-05 US disclosed
US-20050079455-A1 Colour photographic recording material CIBA SPECIALTY CHEMICALS CORP. 2005-04-14 US disclosed
EP-1493057-A1 COLOUR PHOTOGRAPHIC RECORDING MATERIAL Ciba SC Holding AG (CH) 2005-01-05 EP disclosed
EP-1341763-B1 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION CIBA SC HOLDING AG (CH) 2004-06-16 EP disclosed
WO-2003075091-A1 COLOUR PHOTOGRAPHIC RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-09-12 WO disclosed
EP-1341763-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, WITH GLYCIDYL OR ALKYLCARBONYL GROUPS AS FUNCTIONAL INITIATORS FOR CONTROLLED RADICAL POLYMERIZATION Ciba SC Holding AG (CH) 2003-09-10 EP disclosed
WO-2002048109-A2 N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINES AS RADICAL POLYMERIZATION INITIATORS CIBA SPECIALTY CHEMICLAS HOLDING INC. (CH) 2002-06-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070173570-A1 N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization PTGER4, ALKBH3, PIGO MAPT 3644/4885ALDH1A1 737/4885TP53 4722/4885
US-20040049043-A1 N-alkoxy-4,4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization PAOX, ALKBH3, PTGER4 MAPT 3356/4885ALDH1A1 1472/4885TP53 4311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.