Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730653 | 1.00 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL9760026 | 1.00 | MEN1 (0.49) | MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL7294575 | 0.88 | KMT2A (0.42) | MEN1KMT2ASMN1; SMN2CHRM2CHRM3 | |
| SCHEMBL7294562 | 0.88 | KMT2A (0.42) | MEN1KMT2ASMN1; SMN2CHRM2CHRM3 | |
| SCHEMBL7294568 | 0.88 | KMT2A (0.42) | MEN1KMT2ASMN1; SMN2CHRM2CHRM3 | |
| SCHEMBL13566528 | 0.87 | KMT2A (0.41) | MEN1KMT2ASMN1; SMN2L3MBTL1CHRM2 | |
| SCHEMBL14286832 | 0.86 | MEN1 (0.51) | MEN1KMT2ASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL15189740 | 0.84 | L3MBTL1 (0.38) | MEN1KMT2ASMN1; SMN2L3MBTL1CHRM2 | |
| SCHEMBL3872359 | 0.84 | KMT2A (0.46) | MEN1KMT2AL3MBTL1KDM4EBRD4 | |
| SCHEMBL14301507 | 0.79 | OPRM1 (0.40) | KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5041454-A | Stimulate gastrointestinal motility | JANSSEN PHARMACEUTICA N.V. (BE) | 1991-08-20 | — | — | US | disclosed |
| US-4975439-A | Gastrointestinal motility stimulating properties | JANSSEN PHARMACEUTICAL N.V. (BE) | 1990-12-04 | — | — | US | disclosed |