Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MLYCD | O95822 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.43 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183924 | 0.87 | HPGD (0.51) | HPGDALDH1A1MAPTMLYCDLMNA | |
| SCHEMBL2896389 | 0.78 | ACACB (0.45) | HPGDALDH1A1MAPTLMNARAB9A | |
| SCHEMBL5703500 | 0.77 | HPGD (0.73) | HPGDALDH1A1MAPTMLYCDLMNA | |
| SCHEMBL9763616 | 0.76 | HRH3 (0.39) | HPGDALDH1A1MAPTMLYCDLMNA | |
| SCHEMBL20183877 | 0.76 | L3MBTL1 (0.46) | HPGDALDH1A1MAPTMLYCDLMNA | |
| SCHEMBL9672085 | 0.75 | HRH3 (0.49) | MAPTLMNAMEN1KMT2AMMP2 | |
| SCHEMBL9672399 | 0.75 | CA1 (0.53) | HPGDALDH1A1MAPTLMNARAB9A | |
| SCHEMBL3182944 | 0.75 | ALDH1A1 (0.56) | HPGDALDH1A1MAPTMLYCDLMNA | |
| SCHEMBL3610292 | 0.75 | HPGD (0.56) | HPGDALDH1A1MAPTMLYCDLMNA | |
| SCHEMBL3458276 | 0.74 | PTPN11 (0.51) | ALDH1A1MAPTRAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990664-A | Drug for asthma or chronic bronchitis | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |
| EP-0303466-A2 | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-02-15 | — | — | EP | disclosed |