SCHEMBL9760713

SCHEMBL9760713

[N]c1cc(Cl)c(Cl)cc1Br

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
AHR P35869 5/20 0.40
MAPK1 P28482 1/20 0.32
FLT1 P17948 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9760999 0.80 AHR (0.44) AHR
SCHEMBL11281295 0.77 AHR (0.58) AHRMAPK1FLT1
SCHEMBL29600009 0.71 AHR (0.57) AHRMAPK1FLT1
SCHEMBL10872182 0.71 AHR (0.57) AHRMAPK1FLT1
SCHEMBL9760840 0.71 AHR (0.44) AHRMAPK1FLT1
SCHEMBL3850787 0.70 AHR (0.58) AHRMAPK1FLT1
SCHEMBL12402997 0.67 AHR (0.47) AHRMAPK1FLT1
SCHEMBL20241879 0.65 TRPV4 (0.40) AHRMAPK1
SCHEMBL3342238 0.65 GAA (0.53) AHRMAPK1FLT1
SCHEMBL21404025 0.65 AHR (0.40) AHRMAPK1FLT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5021573-A Heterocyclic pigments and dyes SANDOZ LTD. (CH) 1991-06-04 US claimed