Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 6/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | FLT1 | P17948 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.30 |
| ▸ | CDK1 | P06493 | 1/20 | 0.30 |
| ▸ | PIM1 | P11309 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760999 | 0.76 | AHR (0.44) | AHR | |
| SCHEMBL348913 | 0.76 | AHR (0.67) | AHRMAPK1TSHRHSD17B10HPGD | |
| SCHEMBL9760713 | 0.71 | AHR (0.40) | AHRMAPK1FLT1 | |
| SCHEMBL6790265 | 0.65 | — | — | |
| 2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL258301 | 0.62 | AHR (1.00) | AHRMAPK1TSHRHSD17B10HPGD | |
| 2,2',4,4',5,5'-Hexachlorobiphenyl SCHEMBL29367365 | 0.62 | AHR (1.00) | AHRMAPK1TSHRHSD17B10HPGD | |
| SCHEMBL8528070 | 0.59 | CYP3A4 (0.41) | AHRMAPK1TSHRHSD17B10HPGD | |
| SCHEMBL27816053 | 0.59 | AHR (0.47) | AHRMAPK1TSHRHSD17B10HPGD | |
| SCHEMBL5792991 | 0.59 | AHR (0.47) | AHRMAPK1TSHRHSD17B10HPGD | |
| SCHEMBL13197717 | 0.59 | AHR (0.53) | AHRMAPK1TSHRHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5021573-A | Heterocyclic pigments and dyes | SANDOZ LTD. (CH) | 1991-06-04 | — | — | US | claimed |