Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 4/20 | 0.37 |
| ▸ | CES1 | P23141 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30828004 | 1.00 | CES2 (0.37) | CES2CES1TP53LTA4HPCSK9 | |
| SCHEMBL779932 | 1.00 | CES2 (0.37) | CES2CES1TP53LTA4HPCSK9 | |
| SCHEMBL19403477 | 1.00 | CES2 (0.37) | CES2CES1TP53LTA4HPCSK9 | |
| SCHEMBL6002849 | 0.94 | CES2 (0.39) | CES2CES1TP53LTA4HPCSK9 | |
| SCHEMBL17817574 | 0.92 | CES2 (0.41) | CES2CES1TP53TSHRSMN1; SMN2 | |
| SCHEMBL12040835 | 0.92 | CES2 (0.41) | CES2CES1TP53TSHRSMN1; SMN2 | |
| SCHEMBL7329821 | 0.92 | CES2 (0.41) | CES2CES1TP53TSHRSMN1; SMN2 | |
| SCHEMBL9815169 | 0.92 | CES2 (0.41) | CES2CES1TP53TSHRSMN1; SMN2 | |
| SCHEMBL10357516 | 0.92 | CES2 (0.41) | CES2CES1TP53TSHRSMN1; SMN2 | |
| SCHEMBL587114 | 0.92 | CES2 (0.41) | CES2CES1TP53TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117802060-A | Sulfoxide reductase mutant and application thereof in preparation of complex group chiral sulfoxide | 遵义医科大学 | 2024-04-02 | — | — | CN | disclosed |
| CN-117778339-A | Sulfoxide reductase mutant and application thereof in preparation of chiral sulfoxide and sulfinyl ester | 遵义医科大学 | 2024-03-29 | — | — | CN | disclosed |
| US-5068369-A | PROCESS FOR PREPARING CHIRAL SULPHOXIDES | THE BRITISH PETROLEUM COMPANY P.L.C. (GB) | 1991-11-26 | — | — | US | disclosed |
| US-4990676-A | Process for preparing chiral sulphoxides | BRITISH PETROLEUM COMPANY P.L.C. (GB) | 1991-02-05 | — | — | US | disclosed |
| EP-0336538-A1 | Process for preparing chiral sulphoxides | The British Petroleum Company p.l.c. (GB) | 1989-10-11 | — | — | EP | disclosed |