Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | LTA4H | P09960 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17817574 | 0.98 | CES2 (0.41) | CES2CES1SIGMAR1TP53TSHR | |
| SCHEMBL27598273 | 0.98 | CES2 (0.41) | CES2CES1SIGMAR1TP53TSHR | |
| SCHEMBL7329821 | 0.98 | CES2 (0.41) | CES2CES1SIGMAR1TP53TSHR | |
| SCHEMBL587114 | 0.98 | CES2 (0.41) | CES2CES1SIGMAR1TP53TSHR | |
| SCHEMBL9815169 | 0.98 | CES2 (0.41) | CES2CES1SIGMAR1TP53TSHR | |
| SCHEMBL5073895 | 0.98 | CES2 (0.41) | CES2CES1SIGMAR1TP53TSHR | |
| SCHEMBL10357516 | 0.98 | CES2 (0.41) | CES2CES1SIGMAR1TP53TSHR | |
| SCHEMBL12040835 | 0.98 | CES2 (0.41) | CES2CES1SIGMAR1TP53TSHR | |
| SCHEMBL9760714 | 0.94 | CES2 (0.37) | CES2CES1LTA4HSIGMAR1TP53 | |
| SCHEMBL779932 | 0.94 | CES2 (0.37) | CES2CES1LTA4HSIGMAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118754833-A | Synthesis method of aryl benzyl bromosulfoxide alkylation | 南京工业大学 | 2024-10-11 | — | — | CN | disclosed |
| US-20170182009-A1 | SUBSTITUTED BENZOXAZOLONE DERIVATIVES AS ACID CERAMIDASE INHIBITORS, AND THEIR USE AS MEDICAMENTS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-06-29 | — | — | US | disclosed |
| US-9505859-B2 | Process for producing polydienes | BRIDGESTONE CORPORATION (JP) | 2016-11-29 | — | — | US | disclosed |
| CN-104039843-B | Prepare the method for polydiene | BRIDGESTONE CO.,LTD. (JP) | 2016-05-18 | — | — | CN | disclosed |
| EP-2780381-B1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORP (JP) | 2015-10-07 | — | — | EP | disclosed |
| US-20140303327-A1 | Process For Producing Polydienes | BRIDGESTONE CORPORATION (JP) | 2014-10-09 | — | — | US | disclosed |
| EP-2780381-A1 | PROCESS FOR PRODUCING POLYDIENES | Bridgestone Corporation (JP) | 2014-09-24 | — | — | EP | disclosed |
| CN-104039843-A | Process For Producing Polydienes | BRIDGESTONE CORP | 2014-09-10 | — | — | CN | disclosed |
| WO-2013075085-A1 | PROCESS FOR PRODUCING POLYDIENES | BRIDGESTONE CORPORATION (JP) | 2013-05-23 | — | — | WO | disclosed |
| US-20130001472-A1 | THIN FILM AND COMPOUND USED IN THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-01-03 | — | — | US | disclosed |
| EP-1678185-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO [2,1-B] OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005042542-A1 | 2,3-DIHYDRO-6-NITROIMIDAZO (2,1-B) OXAZOLE COMPOUNDS FOR THE TREATMENT OF TUBERCULOSIS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2005-05-12 | — | — | WO | disclosed |
| US-4476929-A | Sulfoxide cosurfactants in enhanced oil recovery processes | PHILLIPS PETROLEUM COMPANY (US) | 1984-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130001472-A1 | THIN FILM AND COMPOUND USED IN THE SAME | NR2E3, NR3C1, NR0B2 | CES2 3551/4885CES1 3488/4885LTA4H 3467/4885 |
| US-20170182009-A1 | SUBSTITUTED BENZOXAZOLONE DERIVATIVES AS ACID CERAMIDASE INHIBITORS, AND THEIR USE AS MEDICAMENTS | ASAH1, ASAH2, ACER2 | CES2 64/4885CES1 30/4885LTA4H 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.