SCHEMBL9760964

SCHEMBL9760964

N=C=O.N=C=O.O=[N+]([O-])c1ccccc1-c1ccccc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.81
TDP1 Q9NUW8 3/20 0.81
PTPN1 P18031 1/20 0.47
CRHBP P24387 1/20 0.44
CRHR2 Q13324 1/20 0.44
ADAMTS4 O75173 1/20 0.44
S100A4 P26447 2/20 0.43
HPGD P15428 1/20 0.43
PTPRC P08575 1/20 0.43
TSHR P16473 1/20 0.43
HSD17B10 Q99714 2/20 0.42
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41
MGAM O43451 1/20 0.41
GAA P10253 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
GUSB P08236 1/20 0.41
F2 P00734 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30196067 0.90 ALDH1A1 (1.00) ALDH1A1TDP1PTPN1CRHBPCRHR2
Benzene SCHEMBL28038982 0.90 ALDH1A1 (1.00) ALDH1A1TDP1PTPN1CRHBPCRHR2
SCHEMBL44392 0.90 ALDH1A1 (1.00) ALDH1A1TDP1PTPN1CRHBPCRHR2
Biphenyl SCHEMBL7209601 0.88 ALDH1A1 (0.96) ALDH1A1TDP1PTPN1CRHBPCRHR2
Hydrogen Sulfide SCHEMBL9671158 0.88 ALDH1A1 (0.96) ALDH1A1TDP1PTPN1CRHBPCRHR2
Water SCHEMBL2045405 0.88 ALDH1A1 (0.96) ALDH1A1TDP1PTPN1CRHBPCRHR2
Water SCHEMBL1828402 0.88 ALDH1A1 (0.96) ALDH1A1TDP1PTPN1CRHBPCRHR2
Methane SCHEMBL2186810 0.88 ALDH1A1 (0.96) ALDH1A1TDP1PTPN1CRHBPCRHR2
SCHEMBL2958562 0.86 ALDH1A1 (0.92) ALDH1A1TDP1PTPN1CRHBPCRHR2
SCHEMBL29180134 0.86 ALDH1A1 (0.92) ALDH1A1TDP1PTPN1CRHBPCRHR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5034426-A Reaction of polyisocyanate, polyol and a chain extender which is also a catalyst because of a tert-amine side chain AIR PRODUCTS AND CHEMICALS, INC. (US) 1991-07-23 US disclosed
US-4937306-A For polyurethanes AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-06-26 US disclosed
US-4908394-A For polyurethane formation AIR PRODUCTS AND CHEMICALS, INC. (US) 1990-03-13 US disclosed
US-4810769-A Process of preparing polyurethanes cured with 2,6-idaminobenzoic acid derivatives and blends of the 2, 4 and 2,6 isomers AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-03-07 US disclosed
EP-0300366-A1 Non-fugitive aromatic diamine catalytic chain extenders AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-01-25 EP disclosed
EP-0300349-A1 Non-fugitive diaminobenzoate catalytic chain extenders AIR PRODUCTS AND CHEMICALS, INC. (US) 1989-01-25 EP disclosed
EP-0293845-A2 Polyurethanes cured with 2,6-diaminobenzoic acid derivatives and blends of the 2,4 and 2,6 isomers AIR PRODUCTS AND CHEMICALS, INC. (US) 1988-12-07 EP disclosed
US-4054556-A Polyurethanes cured with derivatives of 2,4-diamino-benzoic acid E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-10-18 US disclosed
US-4039514-A SUBSTITUTED 2,4-DIAMINOBENZOIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-08-02 US disclosed
US-4032574-A PRODUCTION OF POLYETHERPOLYOLS USEFUL IN PREPARING RIGID POLYURETHANE FOAMS TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) 1977-06-28 US disclosed