Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | CCR6 | P51684 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.33 |
| ▸ | TXNRD3 | Q86VQ6 | 2/20 | 0.33 |
| ▸ | TXNRD2 | Q9NNW7 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10341787 | 0.69 | — | — | |
| SCHEMBL28311107 | 0.69 | — | — | |
| SCHEMBL11565315 | 0.69 | — | — | |
| SCHEMBL10400603 | 0.69 | MAPT (0.41) | MAPTALDH1A1RAB9AKDM4EHTT | |
| SCHEMBL11563958 | 0.69 | ALDH1A1 (0.40) | MAPTALDH1A1KDM4EHTTKMT2A | |
| SCHEMBL10400102 | 0.67 | MAPT (0.41) | MAPTALDH1A1RAB9AHTTKMT2A | |
| SCHEMBL25468130 | 0.66 | — | — | |
| SCHEMBL14938710 | 0.64 | CTSB (0.49) | MAPTALDH1A1KDM4EHTTTXNRD1 | |
| SCHEMBL937505 | 0.64 | MERTK (0.49) | MAPTHTTTXNRD1GAATDP1 | |
| SCHEMBL4874074 | 0.64 | ALDH1A1 (0.41) | MAPTALDH1A1RAB9AKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |