Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761856 | 0.73 | KMT2A (0.40) | KMT2ATSHRMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL4035896 | 0.72 | KMT2A (0.55) | KMT2ATSHRMEN1HSD17B10SMN1; SMN2 | |
| SCHEMBL9760977 | 0.71 | POLB (0.52) | KMT2ATSHRMEN1HSD17B10ALDH1A1 | |
| SCHEMBL3204082 | 0.70 | ALDH1A1 (0.76) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9762223 | 0.70 | ALDH1A1 (0.46) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9762560 | 0.70 | PIK3CB (0.49) | KMT2AMEN1SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7323015 | 0.68 | MAPT (0.46) | SMN1; SMN2ALDH1A1MAPTCYP1A2CYP2C9 | |
| SCHEMBL9762614 | 0.68 | POLB (0.49) | KMT2AMEN1ALDH1A1MAPTCYP1A2 | |
| SCHEMBL312049 | 0.67 | TP53 (0.53) | KMT2ATSHRMEN1ALDH1A1MAPT | |
| SCHEMBL312048 | 0.67 | TP53 (0.53) | KMT2AMEN1ALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |