Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938570 | 0.77 | — | — | |
| SCHEMBL558142 | 0.76 | — | — | |
| SCHEMBL4720897 | 0.69 | KDM4E (0.41) | KDM4E | |
| SCHEMBL16568932 | 0.65 | — | — | |
| SCHEMBL16568933 | 0.65 | — | — | |
| SCHEMBL3063023 | 0.64 | CYP11B2 (0.41) | KDM4E | |
| SCHEMBL315179 | 0.64 | POLB (0.33) | KDM4E | |
| SCHEMBL4021740 | 0.62 | LMNA (0.36) | KDM4E | |
| SCHEMBL445846 | 0.62 | — | — | |
| SCHEMBL38539 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5011847-A | 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO., INC. (US) | 1991-04-30 | — | — | US | disclosed |
| US-5011847-A | 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO., INC. (US) | 1991-04-30 | — | — | US | disclosed |
| US-5001123-A | 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO., INC. (US) | 1991-03-19 | — | — | US | disclosed |
| US-5001123-A | 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO., INC. (US) | 1991-03-19 | — | — | US | disclosed |
| EP-0402156-A1 | New 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | disclosed |
| EP-0402156-A1 | New 2,5-diaryl tetrahydrofurans and analogs thereof as PAF antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | disclosed |
| EP-0402155-A1 | New 2,5-diaryl tetrahydrofurans and analogs therof as PAF antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | disclosed |
| EP-0402155-A1 | New 2,5-diaryl tetrahydrofurans and analogs therof as PAF antagonists | MERCK & CO. INC. (US) | 1990-12-12 | — | — | EP | disclosed |