Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 1/20 | 0.67 |
| ▸ | ESR1 | P03372 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.55 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.55 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.55 |
| ▸ | STS | P08842 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11581098 | 0.94 | CYP1A2 (0.65) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL11771494 | 0.88 | ALDH1A1 (0.70) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL11771674 | 0.88 | ALDH1A1 (0.70) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL5386629 | 0.88 | TDP1 (0.56) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL9005143 | 0.87 | ESR1 (0.70) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL11140799 | 0.87 | LMNA (0.59) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL11730053 | 0.86 | ALDH1A1 (0.67) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL9349732 | 0.86 | ALDH1A1 (0.68) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL9005198 | 0.85 | ESR1 (0.68) | ALDH1A1NPC1MAPTRAB9AESR1 | |
| SCHEMBL8897849 | 0.84 | ALDH1A1 (0.65) | ALDH1A1NPC1MAPTRAB9AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071967-A | Suitable as pigments for coloring polyolefins | CIBA-GEIGY CORPORATION (US) | 1991-12-10 | — | — | US | disclosed |
| US-4997920-A | Dyeing polyolefins | CIBA-GEIGY CORPORATION (US) | 1991-03-05 | — | — | US | disclosed |
| US-4946948-A | COLORING POLYOLEFINS | CIBA-GEIGY CORPORATION (US) | 1990-08-07 | — | — | US | disclosed |