Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4985724 | 0.98 | L3MBTL1 (0.48) | L3MBTL1ALDH1A1AGTR1HSD17B10POLB | |
| SCHEMBL9760740 | 0.86 | HSD17B10 (0.46) | L3MBTL1ALDH1A1HSD17B10POLBAPEX1 | |
| SCHEMBL4983346 | 0.85 | HSD17B10 (0.53) | ALDH1A1HSD17B10POLBAPEX1TDP1 | |
| SCHEMBL9760318 | 0.84 | HSD17B10 (0.48) | L3MBTL1ALDH1A1HSD17B10POLBAPEX1 | |
| SCHEMBL9761313 | 0.82 | SMN1; SMN2 (0.52) | ALDH1A1HSD17B10POLBAPEX1TDP1 | |
| SCHEMBL4985915 | 0.81 | HSD17B10 (0.50) | L3MBTL1ALDH1A1HSD17B10POLBAPEX1 | |
| SCHEMBL3183400 | 0.79 | SMN1; SMN2 (0.55) | ALDH1A1HSD17B10POLBAPEX1TDP1 | |
| SCHEMBL7264731 | 0.79 | HSD17B10 (0.55) | L3MBTL1ALDH1A1AGTR1HSD17B10MAPT | |
| SCHEMBL5050634 | 0.79 | NPSR1 (0.61) | L3MBTL1ALDH1A1HSD17B10POLBAPEX1 | |
| SCHEMBL6943371 | 0.78 | HSD17B10 (0.56) | ALDH1A1HSD17B10POLBAPEX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026863-A | Medicinal products in racemic or enantiomorph form; calcium channel blockers. hypotensive agents, cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1991-06-25 | — | — | US | disclosed |
| US-4983740-A | Multistep; from 2- 2-/2-chloroethoxy/ethoxy!ethanol and potassium phthalimide | ADIR ET COMPAGNIE (FR) | 1991-01-08 | — | — | US | disclosed |
| US-4870091-A | CALCIUM CHANNEL BLOCKERS | ADIR ET CIE (FR) | 1989-09-26 | — | — | US | disclosed |