Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.30 |
| ▸ | IARS2 | Q9NSE4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malonic Acid SCHEMBL11131957 | 0.85 | LMNA (0.53) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL9760918 | 0.85 | LMNA (0.62) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL9761104 | 0.84 | LMNA (0.51) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL9760993 | 0.82 | LMNA (0.47) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL9761210 | 0.80 | LMNA (0.45) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL619959 | 0.80 | LMNA (0.58) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL1389273 | 0.80 | LMNA (0.67) | LMNACYP2C19HIF1AEGFRSRC | |
| Malonic Acid SCHEMBL9760605 | 0.79 | LMNA (0.48) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL8063055 | 0.78 | LMNA (0.53) | LMNACYP2C19HIF1AEGFRSRC | |
| SCHEMBL32668972 | 0.78 | LMNA (0.53) | LMNACYP2C19HIF1AEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5073362-A | DICARBOXYLIC ACID-BIS(3,5-DICARBAMOYL-2,4,6-TRIIODOANILIDES) AND X-RAY CONTRAST MEDIA CONTAINING THEM | SCHERING AKTIENGESELLSCHAFT (DE) | 1991-12-17 | — | — | US | disclosed |