SCHEMBL1389273

SCHEMBL1389273

CN(CC(O)CO)C(=O)c1c(I)c(N)c(I)c(C(=O)NCC(O)CO)c1I

nearest known ligand 0.67

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.67
CYP2C19 P33261 1/20 0.58
HIF1A Q16665 1/20 0.58
EGFR P00533 1/20 0.34
SRC P12931 1/20 0.34
MAP2K1 Q02750 5/20 0.33
MAP2K2 P36507 1/20 0.33
PRKCZ Q05513 1/20 0.33
IARS2 Q9NSE4 1/20 0.33
TYMP P19971 1/20 0.31
CA2 P00918 1/20 0.30
PDE10A Q9Y233 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Malonic Acid SCHEMBL9760918 0.95 LMNA (0.62) LMNACYP2C19HIF1AEGFRSRC
Iotriside SCHEMBL634981 0.91 LMNA (0.68) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL681515 0.88 LMNA (0.50) LMNACYP2C19HIF1ATYMPPDE10A
SCHEMBL12783767 0.86 LMNA (0.74) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL15489157 0.86 LMNA (0.70) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL619959 0.85 LMNA (0.58) LMNACYP2C19HIF1AEGFRSRC
Malonic Acid SCHEMBL9761064 0.85 LMNA (0.51) LMNACYP2C19HIF1A
Malonic Acid SCHEMBL9761104 0.85 LMNA (0.51) LMNACYP2C19HIF1AEGFRSRC
SCHEMBL11292472 0.85 LMNA (0.63) LMNACYP2C19HIF1AEGFRSRC
Malonic Acid SCHEMBL11132766 0.85 LMNA (0.48) LMNACYP2C19HIF1ATYMP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8658239-B2 Coating method for a folded balloon B. BRAUN MELSUNGEN AG (DE) 2014-02-25 US disclosed
US-8658239-B2 Coating method for a folded balloon B. BRAUN MELSUNGEN AG (DE) 2014-02-25 US disclosed
US-8580122-B2 Hybrid chemical/mechanical method and apparatus for inactivating and removing pharmaceuticals and other contaminants from water EARTH RENAISSANCE TECHNOLOGIES, LLC (US) 2013-11-12 US disclosed
US-20130066268-A1 Coating Method for a Folded Balloon B. BRAUN MELSUNGEN AG (DE) 2013-03-14 US disclosed
US-20130066268-A1 Coating Method for a Folded Balloon B. BRAUN MELSUNGEN AG (DE) 2013-03-14 US disclosed
US-8372283-B2 Treatment method reducing wastewater influent chemical/pharmaceuticals before biological reduction to enhance sewage treatment EARTH RENAISSANCE TECHNOLOGIES, LLC (US) 2013-02-12 US disclosed
US-8287940-B2 Coating method for a folded balloon B. BRAUN MELSUNGEN AG (DE) 2012-10-16 US disclosed
US-20120006742-A1 Treatment method reducing wastewater influent chemical/pharmaceuticals before biological reduction to enhance sewage treatment EARTH RENAISSANCE TECHNOLOGIES, LLC (US) 2012-01-12 US disclosed
US-20110247985-A1 Hybrid chemical/mechanical method and apparatus for inactivating and removing pharmaceuticals and other contaminants from water EARTH RENAISSANCE TECHNOLOGIES, LLC (US) 2011-10-13 US disclosed
US-20090054837-A1 Coating Method for a Folded Balloon B. BRAUN MELSUNGEN AG (DE) 2009-02-26 US disclosed
WO-2008104853-A1 PROCESSES FOR THE PREPARATION OF PURE IOVERSOL WOCKHARDT RESEARCH CENTRE (IN) 2008-09-04 WO disclosed