SCHEMBL9761259

SCHEMBL9761259

CCN(CC)C(CCC(C(=O)c1ccc2c(c1)c1ccccc1n2C)N(CC)CC)C(=O)c1ccc2c(c1)c1ccccc1n2C

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.57
ALDH1A1 P00352 4/20 0.48
HPGD P15428 4/20 0.48
CNR2 P34972 4/20 0.47
RORC P51449 1/20 0.47
MAPT P10636 3/20 0.45
LMNA P02545 2/20 0.45
NPC1 O15118 3/20 0.45
RAB9A P51151 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
HSD17B10 Q99714 1/20 0.41
NPY5R Q15761 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9760859 0.78 KDM4E (0.69) KDM4EALDH1A1HPGDCNR2RORC
SCHEMBL29769649 0.76 KDM4E (0.62) KDM4EALDH1A1HPGDCNR2RORC
SCHEMBL28483074 0.76 KDM4E (0.62) KDM4EALDH1A1HPGDCNR2RORC
SCHEMBL2026269 0.76 KDM4E (0.76) KDM4EALDH1A1HPGDRORCMAPT
SCHEMBL4687866 0.76 KDM4E (0.69) KDM4EALDH1A1HPGDCNR2RORC
SCHEMBL27604713 0.74 ALDH1A1 (0.65) KDM4EALDH1A1HPGDCNR2MAPT
SCHEMBL30850787 0.73 KDM4E (1.00) KDM4EALDH1A1HPGDCNR2RORC
SCHEMBL29643237 0.73 KDM4E (0.76) KDM4EALDH1A1HPGDRORCMAPT
SCHEMBL3102894 0.73 KDM4E (1.00) KDM4EALDH1A1HPGDCNR2RORC
SCHEMBL5323335 0.72 KDM4E (0.64) KDM4EALDH1A1HPGDCNR2RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5071888-A Storage stability ASAHI DENKA KOGYO K.K. (JP) 1991-12-10 US disclosed
EP-0171600-A1 Carbazole photoinitiators for the photopolymerization of unsaturated compounds ADEKA ARGUS CHEMICAL CO., Ltd. (JP) 1986-02-19 EP disclosed