Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MITF | O75030 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.30 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.30 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762175 | 0.80 | MAPT (0.33) | MAPTALDH1A1LMNAKCNJ1PKM | |
| SCHEMBL9760948 | 0.74 | CYP1A2 (0.36) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9761847 | 0.74 | NPC1 (0.51) | MAPTLMNAMEN1KMT2ATDP1 | |
| SCHEMBL9762702 | 0.73 | MAPT (0.33) | MAPTALDH1A1TDP1 | |
| SCHEMBL9761370 | 0.70 | KDM4E (0.34) | KDM4EMEN1KMT2A | |
| SCHEMBL30721382 | 0.69 | HRH1 (0.39) | MAPTALDH1A1LMNAKCNJ1PKM | |
| SCHEMBL9761640 | 0.69 | HRH1 (0.33) | — | |
| SCHEMBL10398923 | 0.69 | HRH1 (0.36) | MAPTALDH1A1LMNAKCNJ1 | |
| SCHEMBL9762396 | 0.69 | MAPT (0.33) | MAPT | |
| SCHEMBL9762720 | 0.66 | DHFR (0.33) | ALDH1A1DHFRNPC1MITFRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |