Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.31 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.31 |
| ▸ | GART | P22102 | 1/20 | 0.31 |
| ▸ | HRH1 | P35367 | 7/20 | 0.30 |
| ▸ | HRH2 | P25021 | 2/20 | 0.30 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.30 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.30 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.30 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762396 | 0.79 | MAPT (0.33) | MAPT | |
| SCHEMBL9761376 | 0.73 | MAPT (0.35) | MAPTALDH1A1TDP1 | |
| SCHEMBL9761640 | 0.73 | HRH1 (0.33) | HRH3HRH4HRH1HRH2 | |
| SCHEMBL9761557 | 0.73 | RIPK1 (0.46) | MAPTALDH1A1TDP1 | |
| SCHEMBL9761856 | 0.73 | KMT2A (0.40) | MAPTALDH1A1 | |
| SCHEMBL4269080 | 0.71 | MAPT (0.49) | MAPTALDH1A1TDP1HRH3HRH4 | |
| SCHEMBL10400103 | 0.71 | HRH3 (0.41) | MAPTTDP1HRH3HRH4HRH1 | |
| SCHEMBL7805224 | 0.70 | MAPT (0.39) | MAPTALDH1A1 | |
| SCHEMBL7801102 | 0.69 | MAPT (0.39) | MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL4618823 | 0.69 | MAPT (0.47) | MAPTALDH1A1TDP1HRH3HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |