Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.58 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 6/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760024 | 1.00 | HDAC8 (0.58) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7543605 | 0.89 | HDAC8 (0.59) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7543946 | 0.89 | HDAC8 (0.59) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7589770 | 0.89 | HDAC8 (0.59) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2618100 | 0.89 | HDAC8 (0.59) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7549194 | 0.89 | HDAC8 (0.59) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL9798508 | 0.89 | HDAC8 (0.59) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7547276 | 0.89 | HDAC8 (0.59) | HDAC8HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL10561030 | 0.89 | POLB (0.55) | KMT2ACYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL9798967 | 0.88 | ALDH1A1 (0.58) | HDAC8HDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026863-A | Medicinal products in racemic or enantiomorph form; calcium channel blockers. hypotensive agents, cardiovascular disorders | ADIR ET COMPAGNIE (FR) | 1991-06-25 | — | — | US | disclosed |
| US-4983740-A | Multistep; from 2- 2-/2-chloroethoxy/ethoxy!ethanol and potassium phthalimide | ADIR ET COMPAGNIE (FR) | 1991-01-08 | — | — | US | disclosed |
| US-4870091-A | CALCIUM CHANNEL BLOCKERS | ADIR ET CIE (FR) | 1989-09-26 | — | — | US | disclosed |