Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MLYCD | O95822 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760390 | 0.81 | PDE4A (0.47) | ALDH1A1LMNA | |
| SCHEMBL8732251 | 0.80 | CYP4A11 (0.63) | ALDH1A1MAPTLMNARAB9AHPGD | |
| SCHEMBL1794739 | 0.79 | CYP4A11 (0.61) | ALDH1A1MAPTLMNARAB9AHPGD | |
| SCHEMBL9040138 | 0.78 | RARB (0.53) | ALDH1A1MAPTLMNARCE1MEN1 | |
| SCHEMBL10488145 | 0.78 | THRA (0.49) | ALDH1A1MAPTNPC1LMNARAB9A | |
| SCHEMBL9763439 | 0.78 | THRA (0.49) | ALDH1A1MAPTNPC1LMNARAB9A | |
| SCHEMBL3185726 | 0.77 | THRA (0.61) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9761148 | 0.77 | CYP4A11 (0.58) | ALDH1A1MAPTNPC1LMNARAB9A | |
| SCHEMBL2399439 | 0.77 | THRA (0.61) | ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL9720181 | 0.77 | CA12 (0.45) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990664-A | Drug for asthma or chronic bronchitis | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |
| EP-0303466-A2 | Ethanolamine derivatives | GLAXO GROUP LIMITED (GB) | 1989-02-15 | — | — | EP | disclosed |