Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 9/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761562 | 1.00 | ESR1 (0.41) | ESR1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9547755 | 0.84 | NR5A1 (0.56) | ESR1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9547785 | 0.84 | NR5A1 (0.56) | ESR1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9761610 | 0.84 | NR5A1 (0.56) | ESR1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9547831 | 0.80 | NR5A1 (0.51) | ESR1LMNACHRM2CYP3A4ADORA3 | |
| SCHEMBL9547799 | 0.80 | NR5A1 (0.51) | ESR1LMNACHRM2CYP3A4ADORA3 | |
| SCHEMBL9812231 | 0.80 | NR5A1 (0.64) | ESR1MAPTDRD3NR5A1ESR2 | |
| SCHEMBL9625499 | 0.80 | NR5A1 (0.64) | ESR1MAPTDRD3NR5A1ESR2 | |
| SCHEMBL9547808 | 0.78 | NR5A1 (0.49) | ESR1LMNACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL9547860 | 0.77 | ESR1 (0.47) | ESR1LMNACYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0297745-B1 | OPTICALLY ACTIVE ETHER DERIVATIVES, PREPARATION PROCESSES THEREFOR, LIQUID CRYSTAL MATERIALS AND AN OPTICAL SWITCHING ELEMENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-5013479-A | Aromatic ether esters containing two or three benzene rings | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-05-07 | — | — | US | disclosed |
| EP-0297745-A1 | Optically active ether derivatives, preparation processes therefor, liquid crystal materials and an optical switching element | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1989-01-04 | — | — | EP | disclosed |