Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | AR | P10275 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MITF | O75030 | 2/20 | 0.50 |
| ▸ | GALR2 | O43603 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | XBP1 | P17861 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733033 | 0.88 | AKR1B1 (0.51) | NPC1KMT2AHTTARALDH1A1 | |
| SCHEMBL9762616 | 0.84 | TDP1 (0.57) | NPC1KMT2AHTTALDH1A1CA1 | |
| SCHEMBL396778 | 0.83 | NPC1 (0.54) | NPC1KMT2AALDH1A1SMN1; SMN2MITF | |
| SCHEMBL29396619 | 0.82 | ESR1 (0.64) | KMT2AHTTALDH1A1LMNAHSP90AA1 | |
| SCHEMBL28057459 | 0.82 | NPC1 (0.56) | NPC1ARALDH1A1SMN1; SMN2POLB | |
| SCHEMBL10877588 | 0.81 | GPR35 (0.55) | NPC1KMT2AALDH1A1SMN1; SMN2MITF | |
| SCHEMBL9762646 | 0.81 | KMT2A (0.59) | KMT2AHTTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL11282260 | 0.80 | ALDH1A1 (0.61) | NPC1HTTALDH1A1SMN1; SMN2MITF | |
| SCHEMBL8837568 | 0.80 | ALDH1A1 (0.51) | NPC1KMT2AHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL1465652 | 0.80 | ALDH1A1 (0.51) | NPC1KMT2AALDH1A1SMN1; SMN2MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990699-A | Perfluoroalkylation process | ETHYL CORPORATION (US) | 1991-02-05 | — | — | US | disclosed |