Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 8/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9760461 | 0.89 | TP53 (0.50) | TP53MAPTLMNAENPP2RXFP1 | |
| Hydrochloric Acid SCHEMBL9760488 | 0.89 | POLB (0.48) | TP53MAPTLMNAENPP2POLB | |
| SCHEMBL17966808 | 0.82 | TP53 (0.55) | TP53MAPTLMNAENPP2RXFP1 | |
| SCHEMBL9760898 | 0.76 | SLC6A9 (0.42) | TP53MAPTLMNA | |
| SCHEMBL17966778 | 0.74 | TP53 (0.54) | TP53MAPTLMNAENPP2RXFP1 | |
| SCHEMBL11480609 | 0.73 | SSTR5 (0.57) | TP53MAPTLMNAENPP2RXFP1 | |
| SCHEMBL10446430 | 0.72 | RAB9A (0.42) | TP53LMNA | |
| SCHEMBL17966805 | 0.71 | TP53 (0.59) | TP53MAPTLMNAENPP2RXFP1 | |
| SCHEMBL17966877 | 0.71 | TP53 (0.62) | TP53MAPTLMNAENPP2RXFP1 | |
| Hydrochloric Acid SCHEMBL9741375 | 0.71 | KCNH2 (0.70) | TP53MAPTLMNAENPP2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023256-A | Antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-06-11 | — | — | US | disclosed |