Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | WNK1 | Q9H4A3 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762434 | 0.77 | CDK2 (0.53) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL21189171 | 0.72 | MEN1 (0.55) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL2802597 | 0.71 | CA1 (0.42) | MEN1KMT2AALDH1A1GAAL3MBTL1 | |
| SCHEMBL9762526 | 0.69 | HPGD (0.42) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL5113145 | 0.68 | NPSR1 (0.48) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL9762599 | 0.68 | RIPK1 (0.45) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL9761845 | 0.68 | HPGD (0.60) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL541921 | 0.67 | KMT2A (0.64) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL9761163 | 0.67 | RIPK1 (0.53) | MEN1KMT2APOLBMAPTLMNA | |
| SCHEMBL9762557 | 0.66 | MAPT (0.37) | MEN1KMT2APOLBMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |