Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762599 | 0.72 | RIPK1 (0.45) | HPGDLMNAMAPTPOLBGAA | |
| SCHEMBL9761766 | 0.71 | RIPK1 (0.50) | HPGDLMNAMAPTPOLBGAA | |
| SCHEMBL2050024 | 0.71 | HPGD (0.92) | HPGDPOLBALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL27599943 | 0.70 | HPGD (0.41) | HPGDKMT2AMEN1CDK2 | |
| SCHEMBL17645593 | 0.69 | DYRK1A (0.47) | HPGDMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL9762434 | 0.69 | CDK2 (0.53) | HPGDLMNAMAPTPOLBGAA | |
| SCHEMBL5597711 | 0.68 | HPGD (0.46) | HPGDKMT2AHCAR3KDM4E | |
| SCHEMBL29186500 | 0.68 | DYRK1A (0.46) | HPGDMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL1473102 | 0.68 | LMNA (0.58) | LMNAMAPTPOLBGAARIPK1 | |
| SCHEMBL9761616 | 0.68 | MEN1 (0.49) | HPGDLMNAMAPTPOLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |