Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 5/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.32 |
| ▸ | SLFN12 | Q8IYM2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3965790 | 0.73 | GAA (0.42) | ALDH1A1MAPTHTTLMNAPOLB | |
| SCHEMBL9761096 | 0.70 | ALDH1A1 (0.39) | ALDH1A1RAB9AALDH3A1MAPTMAPK1 | |
| SCHEMBL28920099 | 0.69 | ALDH1A1 (0.33) | ALDH1A1RAB9AMAPTL3MBTL1HTT | |
| SCHEMBL64072 | 0.69 | CYP3A4 (0.33) | ALDH1A1MAPTALOX15LMNACYP1A2 | |
| Propionic Acid SCHEMBL8040155 | 0.68 | ALDH1A1 (0.39) | ALDH1A1MAPTL3MBTL1HTTPOLB | |
| SCHEMBL9627673 | 0.67 | — | — | |
| SCHEMBL28013221 | 0.67 | CYP3A4 (0.32) | ALDH1A1MAPTALOX15LMNACYP1A2 | |
| SCHEMBL28819045 | 0.67 | CYP3A4 (0.32) | ALDH1A1MAPTALOX15LMNACYP1A2 | |
| SCHEMBL27960253 | 0.67 | CYP3A4 (0.32) | ALDH1A1MAPTALOX15LMNACYP1A2 | |
| SCHEMBL28013804 | 0.67 | CYP3A4 (0.32) | ALDH1A1MAPTALOX15LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |