Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126343 | 0.72 | RAB9A (0.33) | ALDH1A1RAB9A | |
| SCHEMBL1126086 | 0.72 | CYP1A2 (0.34) | ALDH1A1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL4266288 | 0.71 | LMNA (0.38) | ALDH1A1KMT2ALMNAKDM4E | |
| SCHEMBL9761658 | 0.70 | ALDH1A1 (0.38) | ALDH1A1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL1979559 | 0.69 | — | — | |
| SCHEMBL1126062 | 0.68 | CYP1A2 (0.34) | ALDH1A1 | |
| SCHEMBL11109785 | 0.67 | MAPT (0.31) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL9762344 | 0.67 | ALDH1A1 (0.38) | ALDH1A1RAB9AMAPTMAPK1L3MBTL1 | |
| SCHEMBL64072 | 0.66 | CYP3A4 (0.33) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL11075168 | 0.66 | PIM3 (0.39) | ALDH1A1MAPTKMT2AMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |