Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762184 | 0.78 | ALDH1A1 (0.31) | MAPTALDH1A1 | |
| SCHEMBL9762405 | 0.77 | MAPT (0.42) | MEN1MAPTKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9761231 | 0.70 | ALDH1A1 (0.41) | MEN1MAPTKMT2AALDH1A1MAPK1 | |
| SCHEMBL9762512 | 0.70 | ALDH1A1 (0.41) | MEN1MAPTKMT2AALDH1A1PKM | |
| SCHEMBL9104518 | 0.67 | MAPT (0.50) | MEN1MAPTKMT2AALDH1A1PKM | |
| SCHEMBL27936376 | 0.66 | MAPT (0.34) | MAPTHTT | |
| SCHEMBL3613033 | 0.66 | MAPT (0.35) | MAPTALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL10400611 | 0.64 | ALDH1A1 (0.49) | MEN1MAPTKMT2AALDH1A1PKM | |
| SCHEMBL28510882 | 0.63 | ALDH1A1 (0.41) | MEN1MAPTKMT2AALDH1A1PKM | |
| SCHEMBL9788027 | 0.60 | F2RL3 (0.34) | MAPTMAPK1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |