Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | IKBKB | O14920 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762626 | 0.78 | MAPT (0.35) | MAPTALDH1A1 | |
| SCHEMBL9761688 | 0.77 | MEN1 (0.31) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL9761629 | 0.77 | MAPT (0.42) | MAPTALDH1A1LMNARECQLNPSR1 | |
| SCHEMBL9762505 | 0.70 | KMT2A (0.44) | MAPTALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL9762512 | 0.70 | ALDH1A1 (0.41) | MAPTALDH1A1NPSR1MEN1KMT2A | |
| SCHEMBL9762128 | 0.69 | KMT2A (0.44) | MAPTALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL9762467 | 0.68 | MAPT (0.35) | MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL9104518 | 0.67 | MAPT (0.50) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL9762656 | 0.67 | MAPT (0.36) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL27936376 | 0.66 | MAPT (0.34) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |