Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9810757 | 0.89 | THRB (0.36) | THRBTHRANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28224414 | 0.86 | THRB (0.40) | THRBTHRASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9601225 | 0.83 | THRB (0.41) | THRBTHRANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL28944794 | 0.82 | THRB (0.47) | THRBTHRAGABRA1GABRB2 | |
| SCHEMBL10576489 | 0.81 | THRB (0.44) | THRBTHRATYMSNPC1RAB9A | |
| SCHEMBL27934453 | 0.79 | THRB (0.47) | THRBTHRAGABRA1GABRB2TYMS | |
| SCHEMBL28297685 | 0.78 | THRB (0.52) | THRBTHRATYMSKDM4EALDH1A1 | |
| SCHEMBL27968998 | 0.77 | THRB (0.45) | THRBTHRAGABRA1GABRB2TYMS | |
| SCHEMBL28889861 | 0.76 | THRB (0.40) | THRBTHRATYMSNPC1RAB9A | |
| SCHEMBL28060385 | 0.75 | THRB (0.38) | THRBTHRANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071888-A | Storage stability | ASAHI DENKA KOGYO K.K. (JP) | 1991-12-10 | — | — | US | disclosed |
| EP-0171600-A1 | Carbazole photoinitiators for the photopolymerization of unsaturated compounds | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1986-02-19 | — | — | EP | disclosed |