Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.36 |
| ▸ | THRA | P10827 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761703 | 0.89 | THRB (0.43) | THRBTHRASMN1; SMN2NPC1RAB9A | |
| SCHEMBL9810759 | 0.80 | THRB (0.44) | THRBTHRAAPPMAPTCACNA1B | |
| SCHEMBL9810765 | 0.80 | THRB (0.44) | THRBTHRAAPPMAPTCACNA1B | |
| SCHEMBL28224414 | 0.76 | THRB (0.40) | THRBTHRASMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL9601225 | 0.74 | THRB (0.41) | THRBTHRAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL28944794 | 0.73 | THRB (0.47) | THRBTHRA | |
| SCHEMBL10576489 | 0.72 | THRB (0.44) | THRBTHRAMAPTSMN1; SMN2NPC1 | |
| SCHEMBL27934453 | 0.70 | THRB (0.47) | THRBTHRASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28297685 | 0.69 | THRB (0.52) | THRBTHRAMAPTKDM4EALDH1A1 | |
| SCHEMBL27968998 | 0.68 | THRB (0.45) | THRBTHRASMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0171600-B1 | CARBAZOLE PHOTOINITIATORS FOR THE PHOTOPOLYMERIZATION OF UNSATURATED COMPOUNDS | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1991-06-12 | — | — | EP | disclosed |