Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.46 |
| ▸ | PTGIR | P43119 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9440886 | 0.83 | PTGIR (0.62) | LTB4RPTGIRHDAC3HDAC4HDAC1 | |
| SCHEMBL9202422 | 0.80 | PTGIR (0.74) | FAAHTP53LTB4RPTGIRLMNA | |
| SCHEMBL9205538 | 0.80 | PTGIR (0.74) | FAAHTP53LTB4RPTGIRLMNA | |
| SCHEMBL9201972 | 0.78 | PTGIR (0.77) | FAAHTP53LTB4RPTGIRLMNA | |
| SCHEMBL9200486 | 0.78 | PTGIR (0.77) | FAAHTP53LTB4RPTGIRLMNA | |
| SCHEMBL8103988 | 0.77 | FAAH (0.61) | FAAHTP53LTB4RPTGIRLMNA | |
| SCHEMBL9842871 | 0.76 | FAAH (0.54) | FAAHTP53LTB4RPTGIRLMNA | |
| SCHEMBL9842920 | 0.76 | FAAH (0.54) | FAAHTP53LTB4RPTGIRLMNA | |
| SCHEMBL22748585 | 0.76 | TLR8 (0.47) | SOAT1 | |
| Methyl Tetradecanoate SCHEMBL28796204 | 0.75 | PPARG (0.56) | FAAHLTB4RLMNAHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | claimed |
| US-5034409-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-07-23 | — | — | US | claimed |
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | disclosed |
| US-5034409-A | Anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-07-23 | — | — | US | disclosed |