Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.54 |
| ▸ | PTGIR | P43119 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9842920 | 1.00 | FAAH (0.54) | FAAHPTGIRTP53LTB4RCA1 | |
| SCHEMBL9843045 | 0.87 | PTGIR (0.64) | FAAHPTGIRLTB4RTSHR | |
| SCHEMBL9842917 | 0.87 | PTGIR (0.64) | FAAHPTGIRLTB4RTSHR | |
| SCHEMBL9205538 | 0.81 | PTGIR (0.74) | FAAHPTGIRTP53LTB4RKDM5B | |
| SCHEMBL9202422 | 0.81 | PTGIR (0.74) | FAAHPTGIRTP53LTB4RKDM5B | |
| SCHEMBL9771000 | 0.79 | KMT2A (0.57) | FAAHPTGIRTP53LTB4RTSHR | |
| SCHEMBL9770961 | 0.79 | KMT2A (0.57) | FAAHPTGIRTP53LTB4RTSHR | |
| SCHEMBL8103988 | 0.76 | FAAH (0.61) | FAAHPTGIRTP53LTB4RKDM5B | |
| SCHEMBL9761768 | 0.76 | FAAH (0.52) | FAAHPTGIRTP53LTB4RPTPRC | |
| SCHEMBL5251124 | 0.76 | HDAC3 (0.53) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | claimed |
| US-4983610-A | BLOOD PLATELET AGGREGATION INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-01-08 | — | — | US | claimed |
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4983610-A | BLOOD PLATELET AGGREGATION INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-01-08 | — | — | US | disclosed |