SCHEMBL9761780

SCHEMBL9761780

CCc1n[nH]c(N(CC)CC)c1[N+](=O)[O-]

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.34
MAPT P10636 4/20 0.33
CASP7 P55210 1/20 0.33
CASP6 P55212 1/20 0.33
TDP1 Q9NUW8 2/20 0.33
GAA P10253 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.32
HPGD P15428 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
KMT2A Q03164 1/20 0.32
GRIN2D O15399 3/20 0.31
GRIN3B O60391 3/20 0.31
GRIN1 Q05586 3/20 0.31
GRIN2A Q12879 3/20 0.31
GRIN2B Q13224 3/20 0.31
GRIN2C Q14957 3/20 0.31
GRIN3A Q8TCU5 3/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
RAB9A P51151 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16832074 0.75 HCAR2 (0.34) ALDH1A1MAPTCASP7CASP6GRIN2D
SCHEMBL16832298 0.75 MAPT (0.46) ALDH1A1MAPTCASP7CASP6GAA
SCHEMBL9760940 0.74 HTT (0.35) ALDH1A1MAPTCASP7CASP6GAA
SCHEMBL3575824 0.70 ALDH1A1 (0.39) ALDH1A1MAPTCASP7CASP6GAA
SCHEMBL1527741 0.69 SMN1; SMN2 (0.41) ALDH1A1MAPTCASP7CASP6TDP1
SCHEMBL27848584 0.69 MAPT (0.35) ALDH1A1MAPTCASP7CASP6GAA
SCHEMBL28823373 0.68 MAPT (0.30) MAPTSMN1; SMN2RAB9ANPC1
SCHEMBL23580730 0.67 DYRK1A (0.43) ALDH1A1MAPTCASP7CASP6GAA
SCHEMBL31498960 0.67 SMN1; SMN2 (0.37) ALDH1A1MAPTCASP7CASP6SMN1; SMN2
SCHEMBL9761859 0.65 ALDH1A1 (0.36) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026694-A Antitumor agents THE BRITISH COLUMBIA CANCER FOUNDATION (CA) 1991-06-25 US disclosed