Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.59 |
| ▸ | PDE4A | P27815 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.58 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 3/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17966778 | 0.86 | TP53 (0.54) | LMNAENPP2TP53MAPT | |
| SCHEMBL30995515 | 0.83 | LMNA (0.63) | LMNAENPP2SMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL22465201 | 0.83 | PTGDR2 (0.48) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9760633 | 0.83 | LMNA (0.61) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL15244777 | 0.80 | LMNA (0.66) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL2247954 | 0.80 | S1PR1 (0.49) | LMNAPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL782939 | 0.78 | CYP1A2 (0.65) | LMNACYP1A2CYP2C19CYP2C9SMN1; SMN2 | |
| SCHEMBL9981519 | 0.78 | LMNA (0.53) | LMNATBXA2R | |
| SCHEMBL1169953 | 0.76 | LMNA (0.70) | LMNAKDM4ECYP1A2CYP2C19CYP2C9 | |
| SCHEMBL9701321 | 0.74 | TBXA2R (0.53) | LMNAPDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5023256-A | Antihistamines | DOMPE FARMACEUTICI S.P.A. (IT) | 1991-06-11 | — | — | US | disclosed |