SCHEMBL9761836

SCHEMBL9761836

O=[N+]([O-])c1ccccc1-c1cc(-c2ccccc2[N+](=O)[O-])cc(-c2ccccc2[N+](=O)[O-])c1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.76
TDP1 Q9NUW8 3/20 0.76
HSD17B10 Q99714 2/20 0.52
TP53 P04637 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C9 P11712 1/20 0.52
MAPK1 P28482 1/20 0.52
CYP2C19 P33261 1/20 0.52
STAT6 P42226 1/20 0.52
HIF1A Q16665 1/20 0.52
PHLPP2 Q6ZVD8 1/20 0.52
S100A4 P26447 2/20 0.50
PTPN1 P18031 1/20 0.50
PTPRC P08575 1/20 0.50
MAOB P27338 1/20 0.49
LMNA P02545 1/20 0.47
MGAM O43451 1/20 0.47
GAA P10253 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16672317 0.92 ALDH1A1 (0.78) ALDH1A1TDP1HSD17B10TP53CYP1A2
SCHEMBL17177867 0.92 ALDH1A1 (0.85) ALDH1A1TDP1HSD17B10TP53CYP1A2
SCHEMBL18419172 0.90 ALDH1A1 (0.75) ALDH1A1TDP1HSD17B10TP53CYP1A2
SCHEMBL18419174 0.87 TDP1 (0.70) ALDH1A1TDP1HSD17B10TP53CYP1A2
SCHEMBL44392 0.86 ALDH1A1 (1.00) ALDH1A1TDP1HSD17B10TP53CYP1A2
Benzene SCHEMBL28038982 0.86 ALDH1A1 (1.00) ALDH1A1TDP1HSD17B10TP53CYP1A2
SCHEMBL30196067 0.86 ALDH1A1 (1.00) ALDH1A1TDP1HSD17B10TP53CYP1A2
SCHEMBL4142462 0.86 TDP1 (0.75) ALDH1A1TDP1HSD17B10TP53CYP1A2
SCHEMBL6067832 0.86 ALDH1A1 (0.63) ALDH1A1TDP1HSD17B10TP53CYP1A2
SCHEMBL20252200 0.86 ALDH1A1 (0.63) ALDH1A1TDP1HSD17B10TP53CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4990421-A High charge generating compound from diazonium salt and aromatic hydroxyamide or imide coupler AGFA-GEVAERT, N.V. (BE) 1991-02-05 US disclosed
EP-0350984-A1 Electrophotographic recording material containing a trisazo dye AGFA-GEVAERT N.V. (BE) 1990-01-17 EP disclosed