Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 13/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 5/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2113104 | 0.84 | CA12 (0.46) | TSHRPOLBMAPTRECQLBLM | |
| SCHEMBL31022685 | 0.84 | CA12 (0.46) | TSHRPOLBMAPTRECQLBLM | |
| SCHEMBL12200278 | 0.83 | CRHBP (0.43) | TSHRPOLBMAPTHSD17B10 | |
| SCHEMBL9834822 | 0.82 | PARP1 (0.53) | PARP1PARP10PARP15TSHRPOLB | |
| SCHEMBL9448428 | 0.81 | PARP1 (0.52) | PARP1PARP10PARP15TSHRPOLB | |
| SCHEMBL3106119 | 0.81 | PARP1 (0.52) | PARP1PARP10PARP15TSHRPOLB | |
| SCHEMBL893991 | 0.78 | PARP1 (0.57) | PARP1TSHRPOLBMAPTHSD17B10 | |
| SCHEMBL4252143 | 0.78 | PARP1 (0.57) | PARP1TSHRPOLBMAPTHSD17B10 | |
| SCHEMBL3158471 | 0.77 | HTR3E (0.47) | PARP1TSHRMAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL3862436 | 0.77 | PARP1 (0.55) | PARP1TSHRPOLBMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5032617-A | Antitumor agents | SRI INTERNATIONAL (US) | 1991-07-16 | — | — | US | claimed |
| WO-1986006628-A1 | BENZAMIDE AND NICOTINAMIDE RADIOSENSITIZERS | SRI INTERNATIONAL (US) | 1986-11-20 | — | — | WO | claimed |