Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 9/20 | 0.40 |
| ▸ | ATM | Q13315 | 3/20 | 0.40 |
| ▸ | BLM | P54132 | 3/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762602 | 0.77 | NPC1 (0.41) | KMT2ACDK2MEN1ATMBLM | |
| SCHEMBL9762608 | 0.76 | NPBWR1 (0.38) | KMT2ACDK2MEN1ATMMAPT | |
| SCHEMBL9761815 | 0.76 | MAPT (0.37) | KMT2ACDK2MEN1ATMBLM | |
| SCHEMBL9761408 | 0.74 | KMT2A (0.41) | KMT2ACDK2MEN1ATMBLM | |
| SCHEMBL9761232 | 0.71 | KMT2A (0.50) | KMT2ACDK2MEN1ATMBLM | |
| SCHEMBL9761702 | 0.69 | NPC1 (0.46) | KMT2ACDK2MEN1ATMBLM | |
| SCHEMBL9761403 | 0.66 | ALDH1A1 (0.32) | MAPTALDH1A1 | |
| SCHEMBL9760943 | 0.65 | KMT2A (0.37) | KMT2ACDK2MEN1NPC1MITF | |
| SCHEMBL11769911 | 0.64 | KMT2A (0.54) | KMT2ACDK2MEN1NPC1RAB9A | |
| SCHEMBL9761831 | 0.63 | CCR6 (0.33) | MAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |