Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.37 |
| ▸ | MEN1 | O00255 | 6/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762597 | 0.70 | KMT2A (0.40) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9762572 | 0.68 | GAA (0.36) | MAPTALDH1A1GAAHTTMAPK1 | |
| SCHEMBL9762566 | 0.68 | NPBWR1 (0.41) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9760943 | 0.68 | KMT2A (0.37) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9761168 | 0.66 | GAA (0.35) | MAPTALDH1A1GAAHTTMAPK1 | |
| SCHEMBL9761511 | 0.65 | KMT2A (0.36) | KMT2AMEN1MAPTLMNAGABBR2 | |
| SCHEMBL9761612 | 0.65 | NPSR1 (0.41) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9761815 | 0.62 | MAPT (0.37) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9762579 | 0.62 | KMT2A (0.46) | KMT2AMEN1MAPTLMNAGABBR2 | |
| SCHEMBL9761608 | 0.62 | MAPT (0.39) | KMT2AMEN1MAPTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |