Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | CCR6 | P51684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761168 | 0.79 | GAA (0.35) | GAAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL9762544 | 0.73 | GAA (0.31) | GAA | |
| SCHEMBL9762169 | 0.68 | KMT2A (0.37) | GAAMAPTALDH1A1MAPK1HTT | |
| SCHEMBL9761177 | 0.68 | — | — | |
| SCHEMBL9761831 | 0.64 | CCR6 (0.33) | MAPTALDH1A1CCR6 | |
| SCHEMBL9760901 | 0.62 | MAPT (0.33) | MAPT | |
| SCHEMBL10400603 | 0.61 | MAPT (0.41) | GAAMAPTALDH1A1HTT | |
| SCHEMBL15932899 | 0.61 | MAPT (0.37) | GAAMAPTALDH1A1HTTCCR6 | |
| SCHEMBL9761467 | 0.58 | ALDH1A1 (0.32) | MAPTALDH1A1 | |
| SCHEMBL9629226 | 0.54 | KDM4E (0.36) | GAAMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |