⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27375407 | 1.00 | — | — | |
| SCHEMBL24767279 | 0.91 | PAOX (0.54) | — | |
| SCHEMBL805275 | 0.84 | — | — | |
| SCHEMBL18536601 | 0.84 | — | — | |
| SCHEMBL9711170 | 0.83 | OPRM1 (0.61) | — | |
| SCHEMBL1746125 | 0.83 | OPRM1 (0.61) | — | |
| SCHEMBL20275250 | 0.82 | GABRP (0.45) | — | |
| SCHEMBL7770091 | 0.82 | — | — | |
| SCHEMBL11200138 | 0.82 | GABRP (0.54) | — | |
| SCHEMBL23396422 | 0.81 | PAOX (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024084363-A1 | USE OF PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 3 COMPOUNDS | PFIZER INC. (US) | 2024-04-25 | — | — | WO | disclosed |
| US-20160303062-A1 | ANTIMICROBIAL COMPOSITIONS AND METHOD OF USE | NATIONAL SCIENCE FOUNDATION | 2016-10-20 | — | — | US | disclosed |
| US-9380784-B2 | Antimicrobial compositions and methods of use | NATIONAL SCIENCE FOUNDATION | 2016-07-05 | — | — | US | disclosed |
| US-20110165261-A1 | ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC (US) | 2011-07-07 | — | — | US | disclosed |
| US-4997842-A | Antiarrhythmia | WARNER-LAMBERT CO. (US) | 1991-03-05 | — | — | US | disclosed |