Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.43 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9761163 | 0.73 | RIPK1 (0.53) | RIPK1MAPTLMNAPOLBGAA | |
| SCHEMBL5099245 | 0.72 | RAB9A (0.58) | NPC1RAB9ATYRMAPTGAA | |
| SCHEMBL29438377 | 0.72 | RAB9A (0.58) | NPC1RAB9ATYRMAPTGAA | |
| SCHEMBL29438374 | 0.72 | RAB9A (0.58) | NPC1RAB9ATYRMAPTGAA | |
| SCHEMBL10465719 | 0.72 | RAB9A (0.52) | NPC1RAB9ATYRMAPTLMNA | |
| SCHEMBL19104738 | 0.71 | NPC1 (0.59) | NPC1RAB9ATYRMAPTLMNA | |
| SCHEMBL19103059 | 0.71 | NPC1 (0.59) | NPC1RAB9ATYRMAPTLMNA | |
| SCHEMBL19381865 | 0.71 | NPC1 (0.59) | NPC1RAB9ATYRMAPTLMNA | |
| SCHEMBL3456389 | 0.71 | RAB9A (0.55) | NPC1RAB9ATYRLMNAPOLB | |
| SCHEMBL13450604 | 0.70 | RAB9A (0.55) | NPC1RAB9ATYRMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |