Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28823373 | 0.73 | MAPT (0.30) | CYP1A2CYP2C9CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL23580730 | 0.71 | DYRK1A (0.43) | CYP1A2MAPTSMN1; SMN2LMNAPOLB | |
| SCHEMBL9762636 | 0.70 | RIPK1 (0.41) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL25554703 | 0.69 | KMT2A (0.58) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL16832074 | 0.68 | HCAR2 (0.34) | CYP1A2CYP2C9CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL16832298 | 0.68 | MAPT (0.46) | KMT2AMEN1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9762557 | 0.68 | MAPT (0.37) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9760940 | 0.66 | HTT (0.35) | CYP1A2CYP2C9CYP2C19MAPTSMN1; SMN2 | |
| SCHEMBL4283112 | 0.65 | HTT (0.51) | KMT2AMEN1MAPTSMN1; SMN2LMNA | |
| SCHEMBL9760928 | 0.65 | KMT2A (0.46) | KMT2AMEN1GABBR2CYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |