Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 6/20 | 0.40 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762363 | 0.70 | KMT2A (0.46) | RIPK1KMT2AMEN1GABBR2CYP1A2 | |
| SCHEMBL22375160 | 0.68 | GAA (0.46) | MAPTGAALMNASMN1; SMN2HTT | |
| SCHEMBL9761816 | 0.66 | GAA (0.45) | KMT2ACYP1A2CYP2C19MAPTGAA | |
| SCHEMBL9762444 | 0.66 | RIPK1 (0.39) | RIPK1KMT2AMEN1GABBR2CYP1A2 | |
| SCHEMBL9762557 | 0.65 | MAPT (0.37) | RIPK1KMT2AMEN1GABBR2CYP1A2 | |
| SCHEMBL9761612 | 0.65 | NPSR1 (0.41) | RIPK1KMT2AMEN1GABBR2CYP1A2 | |
| SCHEMBL9761564 | 0.65 | RIPK1 (0.52) | RIPK1KMT2AMEN1GABBR2CYP1A2 | |
| SCHEMBL9762606 | 0.64 | KMT2A (0.42) | RIPK1KMT2AMEN1GABBR2CYP1A2 | |
| SCHEMBL9761357 | 0.64 | HPGD (0.37) | KMT2AMEN1GABBR2CYP1A2CYP2C9 | |
| SCHEMBL9760917 | 0.63 | GAA (0.45) | KMT2ATDP1MAPTGAALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026694-A | Antitumor agents | THE BRITISH COLUMBIA CANCER FOUNDATION (CA) | 1991-06-25 | — | — | US | disclosed |