SCHEMBL9762406

SCHEMBL9762406

CC(C)Cc1sc([N+](=O)[O-])nc1N(C)C

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9761203 0.76
SCHEMBL9761467 0.73 ALDH1A1 (0.32) ALDH1A1
SCHEMBL9761157 0.71 ALDH1A1 (0.32) ALDH1A1HPGD
SCHEMBL9761419 0.68 CYP1A2 (0.41) ALDH1A1HPGD
SCHEMBL9762473 0.67 KMT2A (0.44)
SCHEMBL9762544 0.66 GAA (0.31)
SCHEMBL10399837 0.62 MAPT (0.34) ALDH1A1HPGD
SCHEMBL9762562 0.62 ALDH1A1 (0.38) ALDH1A1HPGD
SCHEMBL9762597 0.61 KMT2A (0.40) ALDH1A1
SCHEMBL10082423 0.56 FBP1 (0.41) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5026694-A Antitumor agents THE BRITISH COLUMBIA CANCER FOUNDATION (CA) 1991-06-25 US disclosed