Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 3/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9762644 | 0.86 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL27757638 | 0.85 | KCNH2 (0.48) | OPRD1OPRK1KCNH2HSD17B10ALDH1A1 | |
| SCHEMBL9761330 | 0.84 | KCNH2 (0.49) | OPRD1OPRK1KCNH2 | |
| SCHEMBL9761690 | 0.84 | KCNH2 (0.49) | OPRD1OPRK1KCNH2 | |
| SCHEMBL9762432 | 0.84 | KCNH2 (0.49) | OPRD1OPRK1KCNH2 | |
| SCHEMBL17001797 | 0.76 | SMN1; SMN2 (0.38) | OPRD1OPRK1KCNH2ALDH1A1 | |
| SCHEMBL8865490 | 0.75 | HSD17B10 (0.47) | OPRD1OPRK1HSD17B10ALDH1A1TDP1 | |
| SCHEMBL17001812 | 0.75 | HRH1 (0.37) | KCNH2HSD17B10ALDH1A1 | |
| SCHEMBL17001796 | 0.74 | KCNH2 (0.34) | AVPR1AKCNH2 | |
| SCHEMBL20320078 | 0.74 | CARM1 (0.39) | AVPR1AKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5071855-A | Antihistamines, antiallergens | DOMPE FARMACEUTICI SPA (IT) | 1991-12-10 | — | — | US | disclosed |
| EP-0397614-A2 | Pharmacologically active piperdinylimidazopyridines | DOMPE' FARMACEUTICI S.p.A. (IT) | 1990-11-14 | — | — | EP | disclosed |